Congratulations to our BNORC Travel Award Recipients

Congratulations to our Annual Symposium Poster Winners

NEW: BNORC Small Grants Program

Postdoctoral Fellowships in Metabolism, Endocrinology and Obesity at the Boston University School of Medicine

Obesity Journal Club

The Obesity Journal Club is sponsored by the Clinical and Community Research Core of the Boston Nutrition Obesity Research Center (BNORC). The Journal Club is open to faculty, staff and trainees from all institutions including Tufts, BU and Harvard. Please email for additional information and/or to be added to the distribution list.

The Obesity Journal Club will meet on Tuesday, November 24th from 12-1pm in the M&V Room 240 at Tufts (Health Sciences Campus, 136 Harrison Ave)..

Micaela Karlsen, MSPH, Doctoral Candidate at the Friedman School of Nutrition Science and Policy at Tufts, will present and facilitate a discussion of 'Dietary adherence and acceptability of five different diets, including vegan and vegetarian diets, for weight loss: The New DIETs study', by Moore et al., recently published in Eating Behaviors, 2015 Dec;19:33-8.

Faculty and students in the greater Boston area are welcome to attend and present. Those interested in participating may come to Tufts or join the discussion in a webinar style format by dialing in via WebEx. If you would like to receive a PDF of the article that will be discussed and/or a WebEx invitation, please email

Adipose and Metabolic Study Group Seminar:

Tuesday, December 1, 2015 from 10:00 AM – 11:00 AM

Caveolae vs. nucleus? A “new” role of PTRF/Cavin-1 on metabolically regulated ribosomal DNA transcription

Libin Liu, Ph.D.
Instructor, Department of Biochemistry, Boston University School of Medicine

Location: BUMC, EBRC Building, 650 Albany Street, 7th Floor, Room 714

Visit the NORC Central website:

Boston Nutrition Obesity Research Center

The Boston Nutrition Obesity Research Center (BNORC), funded by the National Institutes of Health, NIDDK, is a consortium of institutions -- BMC, Tufts Medical Center and the USDA Human Nutrition Research Center on Aging, the Harvard School of Public Health, and three Harvard Hospitals, the Massachusetts General Hospital (MGH), Beth Israel Deaconess Medical Center, and Brigham and Women’s Hospital.

Our Cores, Pilot and Feasibility Program and annual programs, retreat, seminars and workshops promote inter- and multi-disciplinary research in nutrition and obesity.

Our Center is organized to address four cross-cutting themes that respresent key gaps in understanding the relationship between nutrition and health, and the pathogenesis of obesity and its associated metabolic diseases.

Key areas of nutrition and obesity research across these themes are facilitated and fostered by BNORC Cores:

The Boston Nutrition Obesity Research Center is administratively based at Boston Medical Center and is funded by the National Institutes of Health (NIH/NIDDK) grant P30DK046200. All publications resulting from the utilization of BNORC resources are required to cite this grant in their NIH Funding Acknowledgement and must comply with NIH Public Access Policy.

BNORC Member Retreat

Thank you to everyone who attended the Center’s Retreat on Friday, October 23, 2015.

A special thank you to our presenters and facilitators, including current and past Pilot and Feasibility investigators.

Please send an email to Donna Gibson with any comments, suggestions or feedback about the retreat or the Center.


4/27/2015: As reported on the NIH-NIDDK site:

"Appetite-regulating neural pathway identified"

A team including NIDDK (and BNORC) researchers discovered a neural circuit that controls appetite in the brains of mice. Using a wide array of multidisciplinary techniques, the team found that neurons interacting with a specific receptor in a part of the brain called the hypothalamic paraventricular nucleus and the signals of those neurons to another part of the brain – the lateral parabrachial nucleus – regulate food consumption. Temporarily switching off these neurons in mice that are full makes the mice eat as though they were hungry, while turning them on reduces food consumption in hungry mice as though they were full. Activation of this same satiety-promoting circuit in the absence of food alleviates the unpleasant physical sensations associated with hunger. The findings suggest a potential research approach to treat people with obesity, and could set the foundation for development of a drug to reduce both food consumption and the disagreeable sensation of hunger.

Garfield AS, Li C, Madara JC, Shah BP, Webber E, Steger JS, Campbell JN, Gavrilova O, Lee CE, Olson DP, Elmquist JK, Tannous BA, Krashes MJ, Lowell BB. A neural basis for melanocortin-4 receptor regulated appetite. Nature Neuroscience 2015 April; 10.

Featured Interview

BNORC Researcher

Miguel Alonso-Alonso
MD, MPhil

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